director general of the HIFS
We would like to announce and cordially invite you to the 12th Haploid Markers Conference (HM2023) that will held in Budapest, Hungary. Because of Covid, the meeting was unfortunately postponed from 2020 first to 2021 than to 2022, but now we are very happy to finally be able to hold it in 2023.
HM2023 will be taking place in Budapest, one of the most beautiful cities of Europe. The previous conferences have taken place in the magnificent cities of Berlin, Porto, Innsbruck, Ancona, Brussels, and Bydgoszcz. In the history of Budapest, the year 1872 stands out as a milestone, for it was then that the three separate settlements of Pest, Buda and Óbuda (literally "Old" Buda) were united into one city. Its origins can be traced to the Celtic people who occupied the plains of Hungary from the 4th century BC, until its conquest by the Roman Empire who established the fortress and town of Aquincum on the bank of Danube, today’s Budapest around AD 100, and the subsequent arrival of the Hungarian Conquerors 895 AD.
Budapest officially became the capital city of Hungary in 1873 and underwent rapid growth in size and eminence. This was the city's golden age, and coincided with the Hungarian millennial celebrations in 1896 when the continental Europe's first underground was opened.
The HIFS is the only institution established for forensic expert activities in Hungary, covering the entire country and under the control of the Ministry of the Interior.
The Hungarian Institute for Forensic Sciences located in Budapest, one of the most experienced in studies of haploid markers in Hungary, will be hosting the Conference.
The venue is Hotel Hungaria City Centre in the heart of the Budapest.
Under the motto
Application of haploid markers – innovation and reflection
we want to invite papers –among others- on the following topics:
As in the conferences before renowned plenary speakers will be invited to share their views with us.
The HM2023 has attractive pre-congress and training events.
We hope to see you in Budapest!
Horolma Pamjav (HIFS), Ágota Dobos (HIFS), Lutz Roewer (ILM Berlin) and Walther Parson (ILM Innsbruck)
May 17, 2023
May 18, 2023
from Thursday May 18, 2023 to Saturday May 20, 2023
Hotel Hungaria City Center
Budapest, Rákóczi út 90, 1074
Phone: (+36 1) 889 4400
Please note that the abstract submission deadline is: 10 March, 2023!
31 March, 2023
Budapest sight-seeing tour
Thursday, May 18, 2023 / 10:00 – 13:00
Departure: from Congress Venue.
Departure time: 10:00
Price: EUR 30 (till 01.04.2023), EUR 40 (after 01.04.2023)
The tour takes 3-4 hours with stops at historical places. During the tour, guests can get acquainted with the major attractions of the capital of Hungary. Transfer is included.
(Minimum 20 people)
Danube Bend Tour
Friday, May 19, 2023 / 10:00 – 17:00
Departure: from Congress Venue.
Departure time: 09:00
Price: EUR 60 (till 01.04.2023), EUR 70 (after 01.04.2023)
The program includes a visit to one of most famous historical Baroque artists' village, Szentendre. After sight-seeing in Szentendre the next stop is Visegrad, visiting at the Visegrad Citadel, a formal royal residence and fort. Near the Citadel a traditional 3-course Hungarian lunch is organized for the guests. Transfer is included.
(Minimum 20 people)
Welcome get-together party
Registration / Poster Exhibition / Seminar / Lunch
|09.00-10.00||Presentation of the report|
(including Ethical Challenges and Recommendations)
|10.00-10.15||Short survey of participants|
|12.30-13.00||Promega Lunch Seminar|
|Population genetics I.|
Chairs: Lutz Roewer, Francesc Calafell
|13.45-14.15||A global analysis of matches and mismatches between human genetic and linguistic histories|
|14.15-14.30||The universal Y-SNP database: from a few to a lot and beyond; how to bring it all together|
|14.30-14.45||Combining autosomal ancestry with X and Y AIMs: the VISAGE Enhanced Tool for Appearance and Ancestry|
|14.45-15.00||Population analysis of complete mitogenomes for 334 samples from El Salvador|
|15.00-15.15||Finnish Y chromosome sequencing data suggests dual paths of N1a1 into Finland|
|15.15-15.30||Novel Y chromosomal STRs set demonstrates high resolution of male lineages in North Eurasian human populations|
|15.30-15.45||Optimalization of ancient deep Y haplogroup calling|
|15.45-16.00||Assessment of automated tools for mitochondrial haplogroup prediction|
|16.00-16.15||Sequencing the Lebanese Mitogenome and Y-SNPs: Variants, Haplogrouping and Databasing|
|16.15-16.45||Coffee Break / Poster session|
Chairs: Marta Diepenbroek, Andreas Tillmar
|16.45-17.00||Klessin 1945 - history seen through forensics’ eyes|
|17.00-17.15||Haploid markers aid in the identification of victims of World War II|
Charissa van Kooten
|17.15-17.30||Ancestry analysis of highly degraded remains to assist the identification of fallen Australian service members|
|17.30-17.45||Applications of massively parallel sequencing for unidentified and missing persons casework: An Australian perspective|
|17.45-18.00||When a country exceeds one continent – genetic biogeographical ancestry analysis of remains found at the former Stalag II D prisoner-of-war camp |
|18.00-18.15||Maternal Lineages of Gepids from Transylvania|
Chairs: Walther Parson, Charla Marshall
|09.00-09.30||Mitochondrial DNA in the Age of SNPs |
|09.30-09.45||MITOBOOK: A work management tool for mtDNA analysis|
Cibeles Serna Menor
|09.45-10.00||MITOMETRICS: Studying mitochondrial heteroplasmy along hair shafts|
|10.00-10.15||mtDNA casework through MPS using Reverse Complement PCR and DNAxs as a routine tool|
|10.15-10.30||MPS mitochondrial DNA mixture analysis and Haploid markers based biogeographical investigation; criminal case examples. |
Jord Nagel, Patrick Dieltjes
|10.30-10.45||Comparison and evaluation of commercially available whole mitochondrial genome massively parallel sequencing workflows|
|10.45-10.55||Discrimination of monozygotic twins using mtDNA heteroplasmy through probe capture enrichment and massively parallel sequencing|
|10.55-11.05||Mitochondrial DNA Sequencing from Unbuffered Formalin Fixed Tissues: A Preliminary Study|
|11.05-11.30||Coffee Break / Poster session|
Chairs: Sascha Willuweit, Maarten Larmuseau
|11.30-11.50||Advancing forensic SNP typing: Insights from an interlaboratory study of the FORCE panel|
|11.50-12.05||A combined procedure of WGA and hybrid capture-based MPS enables to genotype 1.2 K identity-informative SNPs from sub-nanogram templates|
|12.05-12.20||Early noninvasive prenatal paternity testing with markers designed for forensic DNA mixture resolution|
|12.20-12.30||Developmental validation of the MGIEasy Signature Identification Library Prep Kit, an all-in-one multiplex system for forensic applications|
|12.30-13.45||Lunch / poster session|
Chairs: Athina Vidaki, Arwin Ralf
|14.00-14.20||Epigenetic aging of the human Y-chromosome in sperm|
|14.20-14.35||A Y-chromosomal MSRE/MDRE multiplex assay for the detection of semen|
|14.35-14.50||Real Time Y Chromosome Enrichment with Nanopore Sequencing|
|14.50-15.05||RM Y-STRs: where do we stand and where are we heading next|
|15.05-15.20||Design and development of novel single multiplex system incorporating 26 rapidly mutating Y-STRs; 26 RM Yplex|
|15.20-15.35||Developmental validation of a high-resolution panel genotyping 639 Y chromosome SNP and InDel markers based on next-generation sequencing|
|15.35-15.50||A novel multiplex of 12 multicopy Y-STRs for forensic application|
|15.50-16.05||Postmortem prevalence of seminal stains and detectability of Y-haplotypes|
|16.05-16.15||Uniq Typer™ Y-10 Genotyping System: Genetic Variation In Southern Africa|
Maria Eugenia D’Amato
|16.15-16.45||Coffee Break / Poster session|
Chairs: Amke Caliebe, Martin Zieger
|16.45-17.05||The discrete Laplace method in court|
|17.05-17.20||Weight of evidence of Y-STR matches computed with the discrete Laplace method: Impact of adding a suspect's profile to a reference database|
Mikkel Meyer Andersen
|17.20-17.35||Haploid marker data analysis using the STRAF 2 software|
|17.35-17.50||The importance of relatedness in Y chromosomal match probability|
|17.50-18.05||Towards probabilistic genotyping for Y-STR profiles |
|18.05-18.20||Is the marker-specific average mutation rate the appropriate parameter for computations in forensics and population genetics? |
|18.20-18.35||Recombulator-X: a fast and user-friendly tool for estimating X chromosome recombination rates in forensic genetics|
|Population genetics II.|
Chairs: Horolma Pamjav, Marcin Wozniak
|09.00-09.20||Combining haploid markers with in-depth family trees to enhance investigative genetic genealogy|
|09.20-09.35||Uniparental genetic diversity of three Hungarian-speaking isolated communities in the Carpathian Basin|
|09.35-09.50||Comparison of Iranian and Mongolian Populations Based on Y-STR Haplotypes Using Machine Learning Methods|
|09.50-10.05||Increasing the resolution of Latin American haplogroup Q sub-lineages using massively parallel sequencing|
|10.05-10.15||Unraveling the history of East Marshal Street Well through ancestry inferences |
|10.15-10.45||Coffee Break / Poster session|
|10.45-11.00||Mitochondrial DNA analysis in the United Arab Emirates populations|
|11.00-11.15||Y-chromosomal landscape in Serbian population groups originating from the Balkan Peninsula|
|11.15-11.30||Unexpected findings at the Amelogenin sex test in forensic paternity/kinship analysis: insights from a 13-year case history|
|11.30-11.45||Canine mitochondrial investigation for breed determination|
|11.45-11.55||Genetic polymorphisms of 23 Y-STR loci in Romanian population|
|11.55-12.15||Wrap-up discussion and closing|
Armed Forces Medical Examiner System's Armed Forces DNA Identification Laboratory (AFMES-AFDIL)
Talk title: Mitochondrial DNA in the Age of SNPs
Department of Evolutionary Biology and Environmental Studies, University of Zurich, Switzerland
Talk title: A global analysis of matches and mismatches between human genetic and linguistic histories
Department of Forensic Genetics, Institute of Legal Medicine and Forensic Sciences, Berlin, Germany
Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria
(the fees inlcude the Hungarian VAT)
|till 01.04.2023||after 01.04.2023|
|Registation fee||EUR 150||EUR 200|
|Registration fee for students with document||EUR 100||EUR 150|
Processing Y chromosome related casework
Wednesday, 17 May, 2023 – 13.00-15.00
Casework experience with mtDNA: reporting of evidence, haplogrouping and ancestry estimation
Wednesday, 17 May, 2023 – 15.30-17.30
Payment should be made by bank transfer to the bank account provided. Please refer to the programme title and the name of the participant in your notice or letter in this form: programme title/name of participant.
The invoice will be issued after the receipt of the fees to the address provided by you.
Payment can also be made by credit card.
To guarantee any registration and/or accommodation the payment of full fee/stay is required. In case of any cancellation up to 01 April, 2023 the costs will be refunded less 30% for administration costs. After this date no any payment (registration, hotel accommodation) can be refunded under any circumstances.
|Hotel Hungaria City Center|
Venue of the conference
Address: Budapest, Rákóczi út 90, 1074, Phone: (+36 1) 889 4400)
|Standard single room||100 EUR /room /night|
|Standard double room||115 EUR /room /night|
|Superior single room||110 EUR /room /night|
|Superior double room||125 EUR /room /night|
|Room rates include: buffet breakfast, WiFi, VAT, local tax.|
Some fall in love with Budapest at first sight, others will only become devotees after a longer stay, but no-one denies that it is one of the most beautifully situated cities in the world. The wide stream of the Danube divides the metropolis of some two million inhabitants into two, the hilly Buda and the flat Pest. The panorama over the Danube and the radial avenue of Andrássy út are on the UNESCO world heritage list. Once you have seen them flood-lit, you will appreciate why.
The story starts on the Buda side when Celts settled on Gellért Hill well before the birth of Christ. This territory was later occupied by the Romans in the 1st century A.D. in their effort to expand the empire's frontiers north to the river Danube. The Roman settlement – Aquincum - grew into a town of 30,000 inhabitants and became the main city of Pannonia province. The Romans constructed paved roads, amphitheatres, bastions and fortified strongholds here, the ruins of which now increase Óbuda district's reputation.
Magyars settling in the territory in the 9th-10th century considered the river Danube the core of their new homeland rather than a natural borderline. The flat areas were populated first, including the large island that once stood where Pest City Centre stands today. The Tatar invasion in the 13th century quickly proved that defence is strategically difficult on a plain. King Béla IV therefore ordered the construction of reinforced stone walls around the towns and set his own royal palace on the top of the protecting hills of Buda.
The town's development was abruptly halted and took a new direction in the 16th century. Formerly rich settlements of Western civilization were gradually turned into vivid oriental "towns" and later abandoned, while the Christian cross was replaced by a new symbol: the crescent of the East. The Turkish occupation lasted for more than 140 years and left only very few marks but much destruction. All the values created by the occupants are linked to water - Turkish thermal baths are the best example. So after the Romans, we "owe a note of thanks" to the Turks for turning our city into a valuable spa resort capitalizing on its rich thermal resources. Some of the pools built in Budapest during the Turkish thraldom are still used today, like Rudas, Király, and another reminder of the Turkish times in Hungary.
The 18th century marked the slow awakening and recovery of the city. On the other hand the 19th century was the age of major changes and witnessed the birth of a completely new city almost from scratch. The hills of Buda and the city walls of Pest no longer provided protection and limited space was a barrier to real development. The core of the shaping metropolis thus moved down from the hill to the plains, making Pest the centre again. 1867 was the year of Reconciliation that brought about the birth of the Austro-Hungarian Monarchy which significantly contributed to the blossoming of the country and its capital city.
In 1873 Buda and Pest were officially merged with the third part, Óbuda (Ancient Buda), thus creating the new metropolis of Budapest. The rapidly growing and flourishing city received new public offices, avenues, channels, public lighting, horse carriageways, a subway, green parks and bridges. By the turn of the century it was a genuine rival to Vienna. Dynamic Pest grew into the country's administrative, political, economic, trade and cultural hub.
The destruction of the Second World War could only be compared to the devastation wrought by the Turkish occupiers. After the war and until May 1990, when the first democratically elected government took power, the country was a victim of communist imperialism. The achievements of the political changes and the past decade, like democracy and a market economy, help to efface the dictatorship of the not so distant past.
Chain bridge from Buda csatle
Parliament at night
Margit bridge from the Buda castle
St Stephen Basilica in Budapest
Margit bridge at night
Chain bridge at night
A rare sight
Convention Budapest Ltd.
H-1143 Besnyői street 13. 1st. floor
Phone: (+36 1) 299 0184, 299 0185
Fax: (+36 1) 299 0187